In a medium saucepan, melt the butter over medium heat. Remove the butter from heat and allow to cool for 2-3 minutes, *see note. Stir Ranch powder, Worcestershire sauce, ground mustard, and garlic powder into the butter until the powder has dissolved and no lumps remain.
Dump the 1 pound bag of mini pretzels into a large bowl, then add the butter/seasoning mixture and gently toss to coat.
Spread pretzels evenly onto a large cookie sheet and bake in the preheated oven for 50 minutes-one hour, stirring every 15 minutes to get a nice, even bake. Once the butter pretzels have dried and are crisp, remove them from the oven and allow to cool.
Store the pretzels in an airtight container and enjoy! Notes and photos below.